SAFE DRUG TAKES OFF TWO POUNDS A WEEK (Dec, 1933)

What drug do you think it was? Meth?

It was definitely Dinitrophenol.  Click here for the Wikipedia entry on its use as a diet aid. Their paper is introduced here

SAFE DRUG TAKES OFF TWO POUNDS A WEEK

Discovery of a drug that enables overweight persons to reduce safely without exercise is reported to the American Medical Association by two California research workers. Experiments conducted by the discoverers, Dr. W. C. Cutting and M. L. Thayer of the Stanford Medical Laboratories, show that daily doses of the drug will remove two pounds of weight a week.

3 comments
  1. Blurgle says: September 23, 20078:16 am

    Cutting was an experimenter in the connection between thyroid problems and obesity in some individuals. He found that although most people lost weight on a reduced-calorie diet, others needed thyroid on top of that.

  2. Jilly says: September 23, 20079:37 pm

    Maybe it is 2,4-Dinitrophenol? I think the article has the co-author cited incorrectly:

    *Tainter ML, Cutting WC. 1933a. Febrile, respiratory and some other actions of dinitrophenol. J Pharmacol Exp Ther 48:410-429.

    *Tainter ML, Cutting WC. 1933b. Miscellaneous actions of dinitrophenol. Repeated administrations, antidotes, fatal doses, antiseptic tests and actions of some isomers. J Pharmacol Exp Ther 49: 187-209.

    *Tainter ML, Cutting WC, Stockton AB. 1934a. Uses of dinitrophenol in nutritional disorders. A
    critical study of clinical results. Am J Public Health 24: 1045-1053.

    *Tainter ML, Cutting WC, Wood DA, et al. 1934b. Di-nitrophenol. Studies of blood, urine, and tissues of dogs on continued medication and after acute fatal poisoning. Arch Pathol 18:881.

    *Tainter ML, Stockton AB, Cutting WC. 1935b. Dinitrophenol in the treatment of obesity: Final report. JAMA 105:332-337.

  3. Hirudinea says: May 30, 20123:45 pm

    @ Jill – Dosn’t 2,4 Dinitrophenol cause hyperthermia?

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